{"id":18157,"date":"2026-11-03T22:15:06","date_gmt":"2026-11-04T05:15:06","guid":{"rendered":"https:\/\/buenosdiasbcs.com\/?p=18157"},"modified":"2026-11-03T22:15:08","modified_gmt":"2026-11-04T05:15:08","slug":"primera-paciente-tratada-con-vacuna-contra-cancer-cuenta-su-experiencia-tras-7-anos-de-recibirla","status":"publish","type":"post","link":"https:\/\/buenosdiasbcs.com\/?p=18157","title":{"rendered":"Primera paciente tratada con vacuna contra c\u00e1ncer cuenta su experiencia tras 7 a\u00f1os de recibirla"},"content":{"rendered":"\n

Donna Gustafson se convirti\u00f3 en la primera persona en el mundo en recibir la vacuna personalizada de ARNm contra el c\u00e1ncer de p\u00e1ncreas<\/h2>\n\n\n\n

Donna Gustafson se convirti\u00f3 en la primera persona en el mundo en recibir la vacuna personalizada de ARNm contra el c\u00e1ncer de p\u00e1ncreas<\/strong> y siete a\u00f1os despu\u00e9s no muestra se\u00f1ales de la enfermedad, que seg\u00fan se esperaba, acabar\u00eda con su vida.<\/p>\n\n\n\n

La mujer de 72 a\u00f1os fue una de las 16 pacientes de un ensayo peque\u00f1o en el Memorial Sloan Kettering Cancer Center y recibi\u00f3 nueve dosis, adem\u00e1s de cirug\u00eda y quimioterapia; la vacuna funcion\u00f3 en ocho de los pacientes, y siete de ellos siguen con vida.<\/p>\n\n\n\n

\u201cHe tenido una calidad de vida del cien por ciento\u201d, cont\u00f3 Donna al medio estadunidense.<\/h3>\n\n\n\n
\"Donna
Donna Gustafson y su esposoNPR<\/figcaption><\/figure>\n\n\n\n

De acuerdo con NPR, la vacuna, llamada autogene cevumeran desarrollada por BioNTech y Genentech<\/a><\/strong>, se dise\u00f1\u00f3 a partir de muestras de su propio tumor para entrenar a sus c\u00e9lulas inmunes a reconocer las prote\u00ednas mutantes de las c\u00e9lulas cancerosas y as\u00ed destruirlas.<\/p>\n\n\n\n

Vinod Balachandran, el cirujano e investigador que dirigi\u00f3 el ensayo, dijo que la respuesta inmunitaria de Gustafson mostr\u00f3 una “expansi\u00f3n de diez mil veces” de las c\u00e9lulas<\/strong> que combaten el c\u00e1ncer, y que se mantuvo alta durante a\u00f1os.<\/p>\n\n\n\n

Vacuna personalizada contra melanoma eleva expectativas<\/h2>\n\n\n\n

Por otro lado, Merck y Moderna informaron que su vacuna personalizada intismeran autogene<\/strong>, administrada junto con Keytruda redujo 42% el riesgo de recurrencia o muerte en comparaci\u00f3n con solo usar el medicamento monoclonal.<\/p>\n\n\n\n

El ensayo de Fase 3 incluy\u00f3 a mil 137 pacientes con melanoma en etapas IIB a IV que se hab\u00edan sometido a una cirug\u00eda para extraer el tumor. Despu\u00e9s de dos a\u00f1os, 82.2% de los pacientes que recibieron la combinaci\u00f3n no present\u00f3 recurrencia de la enfermedad<\/a>, frente a 70.0% de quienes recibieron solo Keytruda.<\/p>\n\n\n\n

Los resultados se presentaron el 24 de octubre en el Congreso de la ESMO en Madrid, luego de que una filtraci\u00f3n oblig\u00f3 a las empresas a adelantar la publicaci\u00f3n de los hallazgos.<\/p>\n\n\n\n

Un impulso federal<\/h2>\n\n\n\n

El Instituto Nacional del C\u00e1ncer (NCI) y la Fundaci\u00f3n para los NIH est\u00e1n planeando una alianza p\u00fablico-privada de 200 millones de d\u00f3lares, la Iniciativa de Vacunas Terap\u00e9uticas contra el C\u00e1ncer (Therapeutic Cancer Vaccines Initiative), para crear redes de ensayos cl\u00ednicos e infraestructura, inform\u00f3 STAT.<\/p>\n\n\n\n

Los investigadores a\u00fan no saben por qu\u00e9 algunos ensayos de vacunas de ARNm fracasan y otros tienen \u00e9xito, indic\u00f3 NPR. Ed, el esposo de Gustafson, describi\u00f3 lo que han significado los \u00faltimos siete a\u00f1os para la pareja: “Ahora simplemente vivimos cada d\u00eda al m\u00e1ximo”<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Donna Gustafson se convirti\u00f3 en la primera persona en el mundo en recibir la vacuna personalizada de ARNm contra el…<\/p>\n","protected":false},"author":2,"featured_media":18158,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-18157","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-salud"],"yoast_head":"\nPrimera paciente tratada con vacuna contra c\u00e1ncer cuenta su experiencia tras 7 a\u00f1os de recibirla - Buenos D\u00edas BCS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/buenosdiasbcs.com\/?p=18157\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Primera paciente tratada con vacuna contra c\u00e1ncer cuenta su experiencia tras 7 a\u00f1os de recibirla\" \/>\n<meta property=\"og:description\" content=\"Donna Gustafson se convirti\u00f3 en la primera persona en el mundo en recibir la vacuna personalizada de ARNm contra el...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/buenosdiasbcs.com\/?p=18157\" \/>\n<meta property=\"og:site_name\" content=\"Buenos D\u00edas BCS\" \/>\n<meta property=\"article:published_time\" content=\"2026-11-04T05:15:06+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-11-04T05:15:08+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/buenosdiasbcs.com\/wp-content\/uploads\/2026\/11\/6aea567227234.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"813\" \/>\n\t<meta property=\"og:image:height\" content=\"542\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Edici\u00f3n Buenos D\u00edas\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Edici\u00f3n Buenos D\u00edas\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/buenosdiasbcs.com\\\/?p=18157#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/buenosdiasbcs.com\\\/?p=18157\"},\"author\":{\"name\":\"Edici\u00f3n Buenos D\u00edas\",\"@id\":\"https:\\\/\\\/buenosdiasbcs.com\\\/#\\\/schema\\\/person\\\/15aedc247eab7070ee5d76d6d069a821\"},\"headline\":\"Primera paciente tratada con vacuna contra c\u00e1ncer cuenta su experiencia tras 7 a\u00f1os de recibirla\",\"datePublished\":\"2026-11-04T05:15:06+00:00\",\"dateModified\":\"2026-11-04T05:15:08+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/buenosdiasbcs.com\\\/?p=18157\"},\"wordCount\":480,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/buenosdiasbcs.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/buenosdiasbcs.com\\\/?p=18157#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/buenosdiasbcs.com\\\/wp-content\\\/uploads\\\/2026\\\/11\\\/6aea567227234.jpeg\",\"articleSection\":[\"Salud\"],\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/buenosdiasbcs.com\\\/?p=18157#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/buenosdiasbcs.com\\\/?p=18157\",\"url\":\"https:\\\/\\\/buenosdiasbcs.com\\\/?p=18157\",\"name\":\"Primera paciente tratada con vacuna contra c\u00e1ncer cuenta su experiencia tras 7 a\u00f1os de recibirla - 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